side effects of amantadine

Daniel Parker

2 min read

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12-03-2025

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Amantadine is a medication primarily used to treat Parkinson's disease and influenza A. While generally well-tolerated, it can cause a range of side effects, some mild and others more serious. Understanding these potential side effects is crucial for safe and effective use. This article provides a comprehensive overview of amantadine's side effects, categorized for easier understanding.

Common Side Effects of Amantadine

These are the side effects most frequently reported by patients taking amantadine. They are usually mild and often subside as your body adjusts to the medication.

• Gastrointestinal Issues: Nausea, vomiting, and diarrhea are common. These are often manageable with dietary adjustments or over-the-counter remedies. If symptoms are severe or persistent, consult your doctor.

• Nervous System Effects: Dizziness, lightheadedness, and insomnia are frequently reported. Staying hydrated and avoiding sudden movements can help mitigate dizziness. For insomnia, discuss sleep hygiene strategies or alternative sleep aids with your doctor.

• Skin Reactions: Dry mouth and skin are common side effects. Staying hydrated and using moisturizing lotions can help alleviate these symptoms.

Less Common but Important Side Effects of Amantadine

While less frequent, these side effects warrant attention and prompt medical consultation if they occur.

• Cardiovascular Effects: Palpitations and edema (swelling) are possible. Report any unusual heart palpitations or swelling in your extremities to your doctor immediately.

• Psychiatric Effects: Amantadine can sometimes cause anxiety, depression, hallucinations, and confusion, particularly in older adults. These are serious side effects requiring immediate medical attention.

• Neurological Effects: Ataxia (loss of coordination), tremor, and involuntary muscle movements are less common but potential side effects. These can impact daily activities and require prompt medical evaluation.

• Liver Issues: In rare cases, amantadine can cause liver damage. Regular liver function tests may be necessary, especially for patients with pre-existing liver conditions.

Serious Side Effects of Amantadine Requiring Immediate Medical Attention

These are rare but potentially life-threatening side effects. Seek immediate medical help if you experience any of the following:

• Severe allergic reactions: These can manifest as hives, swelling of the face, lips, or tongue, difficulty breathing, or a sudden drop in blood pressure. This is a medical emergency.

• Seizures: Amantadine can rarely trigger seizures, especially in individuals with a history of epilepsy or seizure disorders. Seek immediate medical attention if a seizure occurs.

• Stevens-Johnson Syndrome: This is a rare but serious skin reaction that requires immediate medical treatment.

Managing Amantadine Side Effects

Many amantadine side effects can be managed effectively. Here are some tips:

• Stay hydrated: Drinking plenty of fluids can help reduce dry mouth and dizziness.
• Follow your doctor's instructions: Take amantadine exactly as prescribed. Don't adjust your dosage without consulting your doctor.
• Report any side effects: Inform your doctor about any side effects, even if they seem minor.
• Dietary adjustments: If experiencing gastrointestinal issues, try bland foods and avoid trigger foods.
• Lifestyle modifications: Get regular exercise, maintain a healthy diet, and ensure adequate sleep.

When to Contact Your Doctor

Contact your doctor immediately if you experience any concerning side effects, especially those listed under "Serious Side Effects." Regular communication with your healthcare provider is essential for safe and effective amantadine use.

Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with your doctor or other qualified healthcare professional before starting, stopping, or changing any medication. They can assess your individual needs and determine the best course of treatment.