can you overdose on trazodone

Daniel Parker

2 min read

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19-03-2025

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Can You Overdose on Trazodone? Understanding the Risks and What to Do

Trazodone is a commonly prescribed medication used to treat depression and insomnia. While generally safe when taken as directed, yes, it's possible to overdose on trazodone. This article will explore the risks of trazodone overdose, the symptoms to watch for, and what steps to take in an emergency.

Understanding Trazodone and its Potential for Overdose

Trazodone is a serotonin receptor antagonist and reuptake inhibitor (SARI). It works by affecting serotonin levels in the brain. While effective for many, it carries a risk of overdose, particularly when taken in high doses or combined with other medications, especially alcohol or other sedatives.

The risk of a fatal overdose is increased by:

• Taking a significantly higher dose than prescribed: This is the most common cause of trazodone overdose.
• Combining trazodone with other medications: Alcohol, opioids, benzodiazepines, and other central nervous system depressants can dramatically increase the risk of respiratory depression and death when combined with trazodone.
• Pre-existing medical conditions: Individuals with heart conditions, respiratory problems, or liver disease may be more vulnerable to the effects of a trazodone overdose.
• Age and physical health: Older adults and those with weakened physical health are more susceptible to the severe consequences of an overdose.

Symptoms of a Trazodone Overdose

Symptoms of a trazodone overdose can range from mild to severe and can vary depending on the dosage ingested and individual factors. Mild symptoms might include:

• Drowsiness
• Dizziness
• Confusion
• Nausea
• Vomiting

More serious symptoms, indicating a potentially life-threatening overdose, can include:

• Slowed heart rate (bradycardia)
• Low blood pressure (hypotension)
• Respiratory depression (slow or shallow breathing)
• Seizures
• Coma
• Cardiac arrest

What to Do in Case of a Trazodone Overdose

Immediate action is crucial in a suspected trazodone overdose. If you suspect someone has overdosed on trazodone, follow these steps:

1. Call emergency services immediately (911 or your local emergency number). Do not delay; this is a life-threatening situation.
2. Provide as much information as possible to the emergency dispatcher. This includes the amount of trazodone taken, when it was taken, the person's age and weight, any other medications or substances they may have ingested, and any pre-existing medical conditions.
3. If the person is conscious and alert, keep them awake and talking. This can help prevent them from losing consciousness.
4. If the person is unconscious, check their breathing and pulse. Begin CPR if necessary, as instructed by the dispatcher.
5. Follow the instructions given by emergency medical personnel.

Preventing Trazodone Overdose

The best way to prevent a trazodone overdose is to:

• Follow your doctor's instructions carefully. Take only the prescribed dose and do not stop or change your medication without consulting your physician.
• Store your medication safely and out of reach of children and others.
• Never mix trazodone with alcohol or other medications without your doctor's approval.
• Be aware of the signs and symptoms of a trazodone overdose and seek immediate medical attention if you experience them.
• Openly communicate with your doctor or pharmacist about any concerns or side effects.

Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with a healthcare professional for any concerns about your health or medication. Never attempt to self-treat an overdose. Immediate medical attention is critical in cases of suspected overdose.